With one Prevail™ C18 column, retain polar compounds in aqueous mobile phases and hydrophobic compounds in organic mobile phases.
Prevail™ Organic Acid (OA) columns separate common organic acids with an unsurpassed combination of resolution, speed, sensitivity, and simplicity. A simple acidic phosphate buffer and a Prevail™ OA column at ambient temperature will separate 11 short-chain organic acids in less than 6 minutes. Use pH to adjust column selectivity. Lowering the mobile phase pH progressively suppresses the ionization of the carboxylic acids, making them more hydrophobic. This gives you the ability to move these peaks relative to other peaks in the chromatogram, and it simplifies method development.
Get Better Retention Times, Longer Column Life, and Improved Baselines Compared to Traditional Amino Carbohydrate Columns
Quiet Gradient Baselines
Prevail™ Carbohydrate ES Columns are excellent for isocratic separations with common detectors, but the column’s real power shows with the ELSD and a solvent gradient. Enjoy the powerful selectivity, reduced run times, and efficient peaks from gradients while seeing the quiet, stable baselines that maximize sensitivity.
Better Resolution and Peak Shape
Prevail™ Carbohydrate ES Columns are versatile enough for mono- and oligosaccharides and sugar alcohols. They produce single peaks for reducing sugars at ambient temperatures, eliminating the need for column heating.